Dibasic calcium phosphate anhydrous Tablets can be used as the main ingredient in some tablets and as an excipient in some other tablets.
I. As the main ingredient:
Dibasic calcium phosphate anhydrous tablet is generally referred to as Vitamin D2 Calcium Hydrogen Phosphate Tablet and this drug is known to provide calcium supplementation. If the patient is suffering from calcium deficiency, then this drug can be taken under medical supervision for treatment.
Ingredients:
Each tablet contains 500 units of vitamin D2, 150 mg of calcium phosphate (equivalent to 36 mg of calcium). Take by mouth, chew and swallow. Adults take 3-6 tablets 3 times a day.
Effects:
Calcium carbonate in Compound Calcium Hydrogen Phosphate Tablets can participate in the formation of bones and the reconstruction of bone tissues after fracture, can promote the body’s absorption of calcium, and can also maintain the role of neuromuscular excitability; and vitamin D3 can promote the absorption of calcium in the brush border of the small intestinal mucosa, and also increase the renal tubular reabsorption of calcium and phosphorus, so that it can play the role of supplementing the element of calcium. Therefore, Compound Calcium Hydrogen Phosphate Tablet has a better effect of calcium supplementation.
Applicable People:
Compound Calcium Hydrogen Phosphate Tablets are usually used for the prevention and treatment of osteoporosis as well as calcium deficiency in pregnant women, lactating women, menopausal women, the elderly and so on.
II. As an accessory:
Uses:
Its uses include as a filler, binder and disintegrant. It improves the formability and stability of tablets, increases the hardness and homogeneity of tablets, and promotes the release and dissolution of drugs.
- Filler: Sodium hydrogen phosphate anhydrous increases the weight and volume of tablets, making them easier to mold. Its high density and good flowability make tablets more homogeneous and avoid quality problems caused by uneven distribution of drug ingredients.
- Binder: Anhydrous Sodium Hydrogen Phosphate acts as a binder during tablet preparation, helping to form a stable bond between the particles and ensuring the integrity and hardness of the tablet. It can provide sufficient adhesive force so that the tablets are less likely to break during the production process.
- Disintegrant: Anhydrous Sodium Hydrogen Phosphate also acts as a disintegrant in tablets, helping the tablet to break down quickly after administration, thus accelerating the release and absorption of the drug. Its hygroscopic and swelling properties help to disrupt the integrity of the tablet and facilitate the dissolution and absorption of the drug.
Application in preparation process
In the preparation of tablets, anhydrous sodium hydrogen phosphate is usually used in conjunction with other excipients such as starch and powdered sugar. It provides the necessary physical and chemical stability to ensure the quality of tablets during storage and transportation.
In addition, the solubility and swelling properties of anhydrous sodium bisphosphate help regulate the release characteristics of tablets to meet different therapeutic needs.
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